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Search Result

Search Results for " neuropeptide y "

Targets

Neuropeptide Y Receptor Neuropeptide Y Receptor

84

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP1140L Neuropeptide Y (29-64), amide, human acetate Neuropeptide Y Receptor
Neuropeptide Y (29-64), amide, human acetate is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.
TP2206 [Leu31,Pro34]-Neuropeptide Y (porcine) Neuropeptide Y Receptor
High affinity neuropeptide Y Y1 receptor agonist
TP1984L [D-Trp34]-Neuropeptide Y Acetate [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base) Neuropeptide Y Receptor
[D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-...
TP2194L Neuropeptide Y (scrambled) Acetate Pro-Neuropeptide Y (scrambled) Acetate,NPY (scrambled) Acetate Others
Neuropeptide Y (scrambled) Acetate (Pro-Neuropeptide Y (scrambled) Acetate) is a scrambled peptide of Neuropeptide Y that has been implicated in Alzheimer's disease (AD) and may have neuroprotective effects.
T36446 Neuropeptide Y (human) (TFA)
Neuropeptide Y (human) TFA, a compound implicated in Alzheimer's disease (AD), exhibits protective effects against β-Amyloid toxicity in rat cortical neurons.
T36447 Neuropeptide Y 13-36 (porcine)
Neuropeptide Y 13-36 (porcine) is a selective neuropeptide Y2 receptor agonist.
T36445 Neuropeptide Y (3-36) (human, rat)
Neuropeptide Y (3-36) (human, rat) is a metabolite of neuropeptide Y (NPY) generated by dipeptidyl peptidase-4 (DPP4). Known as a selective Y2 receptor agonist, Neuropeptide Y (3-36) (human, rat) effectively reduces the ...
TP1140 Neuropeptide Y (human) Human neuropeptide Y (29-64),Neuropeptide Y (29-64), amide, human
Neuropeptide Y (29-64), amide, human is a biologically active 36-amino acid peptide.
TP1818 Neuropeptide Y(29-64)
Neuropeptide Y(29-64) is a 36 amino acid peptide, a fragment of Neuropeptide Y.
TP1681 Neuropeptide Y (22-36)
Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the centra...
TP2194 Neuropeptide Y (scrambled) Others
Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that exerts its activity via G-protein-coupled receptors. NPY is widely distributed in the peripheral and central nervous systems. It modulates a variety of physiologi...
T35599 Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)
Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. NPY (3-36) is an endogenous peptide produced ...
TP1984 [D-Trp34]-Neuropeptide Y
Potent neuropeptide Y (NPY) Y5 receptor agonist (pEC50 values are 7.82, 6.28, 6.44 and > 6 at rat Y5, Y4, Y1 and Y2 receptors respectively) that displays > 26-fold, > 1000-fold and > 1000-fold selectivity over Y1, Y2 and...
TP1081 Neuropeptide Y (13-36), amide, human Neuropeptide Y (13-36), human
Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.
TP1985 [Leu31,Pro34]-Neuropeptide Y(human,rat) [Leu31,Pro34]-Neuropeptide Y (human, rat)
High affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Also shows affinity for Y4 and Y5 receptors.
TP1338 Neuropeptide Y (29-64), amide, human TFA
Neuropeptide Y (29-64), amide, human (TFA) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.It is showed that Neuropeptide Y (29-64), amide, human (TFA) is able to prot...
T23094 NTNCB hydrochloride Others , Neuropeptide Y Receptor
NTNCB hydrochloride is an antagonist of neuropeptide Y (NPY) Y5 receptor.
TQ0286 MK-0557 Neuropeptide Y Receptor
MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).
T8963 CYM2503 Neuropeptide Y Receptor
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthosteric galanin binding site of the receptor (as measured by ...
T75734 Neuropeptide Y, porcine
Neuropeptide Y (porcine), a peptide found in the porcine brain, effectively inhibits secretin-stimulated pancreatic secretion [1].
T10539 BIBO3304 TFA Neuropeptide Y Receptor
BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 receptor).
T17222 Velneperit S2367 Neuropeptide Y Receptor
Velneperit (S2367) is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
T5587 CGP71683 hydrochloride CGP71683A Neuropeptide Y Receptor
CGP71683 hydrochloride (CGP71683A) is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
TP1380 Galanin (1-16), mouse, porcine, rat Neuropeptide Y Receptor
Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with high biological activity on locus coeruleus neurons.
T75735 Neuropeptide Y, porcine TFA
Neuropeptide Y, porcine TFA, a peptide found in the pig's brain, effectively inhibits secretin-stimulated pancreatic secretion [1].
T1997 JNJ-31020028 JNJ 31020028 Neuropeptide Y Receptor
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
T5455 HT-2157 SNAP37889,SNAP-37889 Neuropeptide Y Receptor
HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.
T76355 Neuropeptide Y (3-36) (porcine)
Neuropeptide Y (3-36) (porcine) acts as an agonist for the Y2 subtype of the neuropeptide Y (NPY) receptor, effectively stimulating feeding behavior in rats. This compound exhibits high selectivity for the Y2 receptor co...
T76357 Neuropeptide Y (18-36) (porcine)
Neuropeptide Y (18-36) (porcine) acts as a competitive antagonist of the neuropeptide Y (NPY) cardiac receptor, effectively blocking the attachment of I-NPY to cardiac ventricular membranes. Its action is concentration-d...
T75911 [D-Trp34]-Neuropeptide Y TFA
[D-Trp34]-Neuropeptide Y TFA acts as a potent and selective agonist for the neuropeptide Y (NPY) Y5 receptor, demonstrating significantly lower potency at the NPY Y1, Y2, Y4, and Y6 receptors. It has been observed to sig...
T75730 [D-Arg25]-Neuropeptide Y (human)
[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY), a Y1 receptor selective agonist, plays a role in Alzheimer's disease (AD) and safeguards rat cortical neurons from β-Amyloid toxicity [1].
T76358 Neuropeptide Y (1-24) (human)
Neuropeptide Y (1-24) (human) is a neuropeptide that inhibits the electrically stimulated twitch response in rat vas deferens and activates neurons in the rat CA3 region of the dorsal hippocampus in vivo following N-meth...
T76356 Neuropeptide Y (2-36) (porcine)
Neuropeptide Y (2-36) (porcine) is a pig-sourced peptide closely resembling its rat and human counterparts with 97.14% homology. It acts as an agonist for rat neuropeptide receptors Y5, Y2, and Y1, demonstrating EC50 val...
T83677 Neuropeptide Y (porcine, bovine) TFA NPY (porcine, bovine)
Neuropeptide Y (NPY), a neuropeptide, plays roles in regulating appetite, vasoconstriction, cardiac contractility, and intestinal secretion, acting as an agonist for NPY receptors Y1, Y2, and Y5. Expressed ubiquitously, ...
T74350 Neuropeptide Y Y1 receptor antagonist 1
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, serves as a powerful antagonist against the neuropeptide Y Y1 receptor (Y1R), exhibiting a Kᵢ value of 0.19 nM [1]. It should be stored in condi...
TP1059 Peptide YY (PYY) (3-36), human Peptide YY (3-36) Neuropeptide Y Receptor
Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.
T75912 [Leu31,Pro34]-Neuropeptide Y(human,rat) TFA
[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA acts as a specific agonist for the neuropeptide Y Y1 receptor, while also activating receptors Y4 and Y5. This compound is known to elevate blood pressure in anesthetized rats ...
T80143 Galanin (1-13)-Neuropeptide Y (25-36) amide Neuropeptide Y Receptor
Galanin (1-13)-Neuropeptide Y (25-36) amide exhibits high-affinity binding to galanin receptors, similar to that of galanin itself [1].
T8456 GALNON Neuropeptide Y Receptor
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties
T12895 SHA 68 Neuropeptide Y Receptor
SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR)(NPSR Asn107 and NPSR Ile107 with IC50s of 22.0 and 23.8 nM, respectively).
T23087 NPY 5RA972 Neuropeptide Y Receptor
neuropeptide Y Y5 receptor antagonist
T21611L BWX 46 Acetate BWX 46 Acetate(172997-92-1 Free base) Neuropeptide Y Receptor
BWX 46 Acetate is a potent, highly selective neuropeptide Y (NPY) receptor agonist with IC50 of 0.5 nM.
T71321 (S)-VU0637120 Others
(S)-VU0637120 is a selective neuropeptide Y(4)R-mutant antagonist used in the study of metabolic disorders.
T77783 WAY-639889 Neuropeptide Y Receptor
WAY-639889 is a small molecule compound with selective and potent inhibitory effects on neuropeptide Y-5 receptors.
T23349 SF 11 Others
SF 11 is a potent and brain penetrant neuropeptide Y Y2 receptor antagonist with IC50 of 199 nM. Antidepressant-like activity
TP1137L Pancreatic Polypeptide (human) acetate Neuropeptide Y Receptor
Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.
T71749 SF-22 Neuropeptide Y Receptor
SF-22 is a neuropeptide Y receptor (Y2R) antagonist that crosses the blood-brain barrier and has potential anti-inflammatory activity for the study of diseases associated with neurological disorders.
TP1858L Phe-Met-Arg-Phe, amide acetate Phe-Met-Arg-Phe, amide acetate（64190-70-1 freebase) Potassium Channel
Phe-Met-Arg-Phe, amide acetate dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons. This peptide appears to localize with neuropeptide Y in some regions of the brain.
T15679 L 152804 Neuropeptide Y Receptor
L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice.
T26801 BIBP3226 BIBP 3226,BIBP-3226
BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor Y1 and the neuropeptide FF receptor.

Compounds

Neuropeptide Y (29-64), amide, human acetate
TP1140L
Synonym:
Target: Neuropeptide Y Receptor
[Leu31,Pro34]-Neuropeptide Y (porcine)
TP2206
Synonym:
Target: Neuropeptide Y Receptor
[D-Trp34]-Neuropeptide Y Acetate
TP1984L
Synonym: [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)
Target: Neuropeptide Y Receptor
Neuropeptide Y (scrambled) Acetate
TP2194L
Synonym: Pro-Neuropeptide Y (scrambled) Acetate,NPY (scrambled) Acetate
Target: Others
Neuropeptide Y (human) (TFA)
T36446
Synonym:
Target:
Neuropeptide Y 13-36 (porcine)
T36447
Synonym:
Target:
Neuropeptide Y (3-36) (human, rat)
T36445
Synonym:
Target:
Neuropeptide Y (human)
TP1140
Synonym: Human neuropeptide Y (29-64),Neuropeptide Y (29-64), amide, human
Target:
Neuropeptide Y(29-64)
TP1818
Synonym:
Target:
Neuropeptide Y (22-36)
TP1681
Synonym:
Target:
Neuropeptide Y (scrambled)
TP2194
Synonym:
Target: Others
Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)
T35599
Synonym:
Target:
[D-Trp34]-Neuropeptide Y
TP1984
Synonym:
Target:
Neuropeptide Y (13-36), amide, human
TP1081
Synonym: Neuropeptide Y (13-36), human
Target:
[Leu31,Pro34]-Neuropeptide Y(human,rat)
TP1985
Synonym: [Leu31,Pro34]-Neuropeptide Y (human, rat)
Target:
Neuropeptide Y (29-64), amide, human TFA
TP1338
Synonym:
Target:
NTNCB hydrochloride
T23094
Synonym:
Target: Others, Neuropeptide Y Receptor
MK-0557
TQ0286
Synonym:
Target: Neuropeptide Y Receptor
CYM2503
T8963
Synonym:
Target: Neuropeptide Y Receptor
Neuropeptide Y, porcine
T75734
Synonym:
Target:
BIBO3304 TFA
T10539
Synonym:
Target: Neuropeptide Y Receptor
Velneperit
T17222
Synonym: S2367
Target: Neuropeptide Y Receptor
CGP71683 hydrochloride
T5587
Synonym: CGP71683A
Target: Neuropeptide Y Receptor
Galanin (1-16), mouse, porcine, rat
TP1380
Synonym:
Target: Neuropeptide Y Receptor
Neuropeptide Y, porcine TFA
T75735
Synonym:
Target:
JNJ-31020028
T1997
Synonym: JNJ 31020028
Target: Neuropeptide Y Receptor
HT-2157
T5455
Synonym: SNAP37889,SNAP-37889
Target: Neuropeptide Y Receptor
Neuropeptide Y (3-36) (porcine)
T76355
Synonym:
Target:
Neuropeptide Y (18-36) (porcine)
T76357
Synonym:
Target:
[D-Trp34]-Neuropeptide Y TFA
T75911
Synonym:
Target:
[D-Arg25]-Neuropeptide Y (human)
T75730
Synonym:
Target:
Neuropeptide Y (1-24) (human)
T76358
Synonym:
Target:
Neuropeptide Y (2-36) (porcine)
T76356
Synonym:
Target:
Neuropeptide Y (porcine, bovine) TFA
T83677
Synonym: NPY (porcine, bovine)
Target:
Neuropeptide Y Y1 receptor antagonist 1
T74350
Synonym:
Target:
Peptide YY (PYY) (3-36), human
TP1059
Synonym: Peptide YY (3-36)
Target: Neuropeptide Y Receptor
[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA
T75912
Synonym:
Target:
Galanin (1-13)-Neuropeptide Y (25-36) amide
T80143
Synonym:
Target: Neuropeptide Y Receptor
GALNON
T8456
Synonym:
Target: Neuropeptide Y Receptor
SHA 68
T12895
Synonym:
Target: Neuropeptide Y Receptor
NPY 5RA972
T23087
Synonym:
Target: Neuropeptide Y Receptor
BWX 46 Acetate
T21611L
Synonym: BWX 46 Acetate(172997-92-1 Free base)
Target: Neuropeptide Y Receptor
(S)-VU0637120
T71321
Synonym:
Target: Others
WAY-639889
T77783
Synonym:
Target: Neuropeptide Y Receptor
SF 11
T23349
Synonym:
Target: Others
Pancreatic Polypeptide (human) acetate
TP1137L
Synonym:
Target: Neuropeptide Y Receptor
SF-22
T71749
Synonym:
Target: Neuropeptide Y Receptor
Phe-Met-Arg-Phe, amide acetate
TP1858L
Synonym: Phe-Met-Arg-Phe, amide acetate（64190-70-1 freebase)
Target: Potassium Channel
L 152804
T15679
Synonym:
Target: Neuropeptide Y Receptor
BIBP3226
T26801
Synonym: BIBP 3226,BIBP-3226
Target:
1 2

Recombinant Proteins

Species：
Human (3)
Mouse (1)
Expression System：
E. coli (2)
HEK293 Cells (2)
Tag：
N-10xHis (2)
C-6xHis (1)
N-hFc (1)
Cat No. Product Name Species Expression System
TMPY-00286 Neuropeptide Y Protein, Human, Recombinant (hFc) Human HEK293 Cells
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ...
TMPJ-00007 NPY Protein, Human, Recombinant (His) Human HEK293 Cells
Pro-Neuropeptide Y (NPY) is a member of the NPY family. NPY is a secreted protein and is one of the most abundant peptides in the nervous system. It also can be found in some chromaffin cells of the adrenal medulla. NPY ...
TMPH-02809 NPY2R Protein, Mouse, Recombinant (His) Mouse E. coli
Receptor for neuropeptide Y and peptide YY. NPY2R Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 11.0 kDa and the accession number is P972...
TMPH-01767 NPY2R Protein, Human, Recombinant (His) Human E. coli
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY a...
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